Description

Research Use Only

This product is intended for laboratory research use only. It is not intended for human consumption, therapeutic, or diagnostic use. Handle in accordance with good laboratory practices.

What Is LL-37?

LL-37 is a synthetic 37-amino-acid cathelicidin peptide supplied as a high-purity lyophilized research material for in vitro and analytical laboratory applications.

Overview

LL-37 is a synthetic 37-amino-acid cathelicidin peptide referenced in published preclinical literature on host defense mechanisms and innate immunity. Manufactured to high-purity standards (≥99%) with independent third-party analytical verification, it is supplied as a 5 mg lyophilized powder for qualified laboratory and research use.

History

LL-37 is the sole human member of the cathelicidin family of antimicrobial peptides, cleaved from the precursor protein hCAP18. It was first identified and isolated through structural studies examining natural defense mechanisms, and has since been extensively characterized in published scientific literature for its role in cellular signaling and host-pathogen interactions.

Research Findings

Preclinical research models heavily utilize LL-37 to examine immunological signaling pathways, inflammatory cascade modulation, and neutralizing interactions with lipopolysaccharides. Additional scientific literature focuses on its structural influence in tissue response mechanisms, re-epithelialization dynamics, cell-membrane interactions, and comparative peptide characterization assays.