Description

Research Use Only

This product is intended for laboratory research use only. It is not intended for human consumption, therapeutic, or diagnostic use. Handle in accordance with good laboratory practices.

What Is Epithalon?

Epithalon (also known as Epitalon) is a synthetic tetrapeptide composed of four amino acids (Ala-Glu-Asp-Gly) supplied as a high-purity lyophilized research material for in vitro and analytical laboratory applications in cellular longevity and peptide signaling.

Overview

Epithalon is a synthetic 4-amino-acid peptide referenced in published preclinical literature on telomere dynamics, cellular senescence, and neuroendocrine signaling. Manufactured to high purity standards (≥99%) with independent third-party analytical verification, it is supplied as a high-purity lyophilized powder vial for qualified laboratory and research use.

History

Epithalon was originally synthesized by Professor Vladimir Khavinson and researchers at the St. Petersburg Institute of Bioregulation and Gerontology. It was designed as a synthetic peptide mimic of epithalamin, a natural pineal gland extract, to investigate the structural mechanisms through which short pineal-derived peptide sequences regulate cellular homeostasis and neuroendocrine function.

Research Findings

Preclinical research models heavily utilize Epithalon to evaluate its role in stimulating telomerase activity, maintaining telomere length, and delaying cellular senescence in vitro. Scientific literature focuses on its influence on pineal gland function, melatonin synthesis regulation, antioxidant enzyme activity, and the normalization of circadian and endocrine signaling pathways in laboratory studies.