Description

Research Use Only

This product is intended for laboratory research use only. It is not intended for human consumption, therapeutic, or diagnostic use. Handle in accordance with good laboratory practices.

What Is AOD 9604?

AOD 9604 is a synthetic peptide fragment derived from the C-terminal domain of human growth hormone (hGH), specifically encompassing amino acids 177 to 191 with an added tyrosine residue at the N-terminus. It is supplied as a high-purity lyophilized material for in vitro and analytical laboratory applications.

Overview

AOD 9604 is a modified 16-amino-acid peptide fragment of human growth hormone referenced in published preclinical literature regarding lipid metabolism and adipose tissue regulation. Manufactured to high purity standards (≥99%) with independent third-party analytical verification, it is supplied as a lyophilized powder vial for qualified laboratory and research use.

History

AOD 9604 (originally known as Metabolic Fragment) was developed in the 1990s as part of ongoing scientific efforts to isolate the specific functional sequences of human growth hormone responsible for fat-reducing activity while separating them from the growth-promoting and hyperglycemic effects of the full-length hormone. Structural modifications, including the addition of a terminal tyrosine, were introduced to enhance metabolic stability and resistance to enzymatic degradation in laboratory assays.

Research Findings

Preclinical research models heavily utilize AOD 9604 to investigate mechanisms of lipolysis promotion and the inhibition of lipogenesis in fat tissue. Scientific literature focuses on its interaction with lipid-regulating pathways, examining how specific peptide fragments mimic the fat-reducing signaling cascades of natural growth hormone without stimulating insulin-like growth factor (IGF-1) receptors or affecting systemic growth.